Make Bioprinting Easy

Make Bioprinting Easy

Standardizing bioprinting

to make regenerative medicine

the medicine of tomorrow

The Complexity Behind Advanced Multi-Dimensional Cellular Models.

Advanced 3D cellular models based on complex bioprinted scaffolds provide unprecedented opportunities to develop predictive models for drug discovery and disease understanding, while also enabling the advancement of next-generation implantable medical devices.

However, recreating multi-tissue structures, vascular networks, and the extracellular matrix with sufficient accuracy remains a major bottleneck. Current approaches often struggle to reproduce:

  • Intricate heterotypic organization
  • Hierarchical architecture of living tissues.
  • Limited control over nanoscale features—essential for guiding cell behavior and function

The Complexity Behind Advanced Multi-Dimensional Cellular Models.

Advanced 3D cellular models based on complex bioprinted scaffolds provide unprecedented opportunities to develop predictive models for drug discovery and disease understanding, while also enabling the advancement of next-generation implantable medical devices.

However, recreating multi-tissue structures, vascular networks, and the extracellular matrix with sufficient accuracy remains a major bottleneck. Current approaches often struggle to reproduce:

  • Intricate heterotypic organization
  • Hierarchical architecture of living tissues.
  • Limited control over nanoscale features—essential for guiding cell behavior and function
  • ORGAN ON CHIP
  • ORGANOID

PRODUCTS

Bioprinters

Multi Technology in one solution

AI-Powered Software

Design complex printing pathway

Biomaterials

GMP bioink stabilizers

SERVICES

Makby Material Labs

Material Characterization for 3D Bioprinting

Makby Pre-Clinical

In vitro and In vivo Validation

APPROACH

Multimodal Bioprinting

AI-Driven Design

Clinical Translation

  • Expertise in method development across diverse biomaterials, with deep understanding of rheological properties to ensure reliable extrusion and deposition
  • Strong knowledge of advanced fabrication technologies, including extrusion-based bioprinting, electrospinning, melt electrowriting, FDM, and pellet-based systems
  • Expertise in method development across diverse biomaterials, with deep understanding of rheological properties to ensure reliable extrusion and deposition
  • Strong knowledge of advanced fabrication technologies, including extrusion-based bioprinting, electrospinning, melt electrowriting, FDM, and pellet-based systems
  • Processing of MRI and CT data to enable patient-specific bioprinting strategies
  • Computational design of complex, multi-material spatial distributions
  • Advanced algorithms to generate precise printing patterns that replicate target tissue structures
  • Processing of MRI and CT data to enable patient-specific bioprinting strategies
  • Computational design of complex, multi-material spatial distributions
  • Advanced algorithms to generate precise printing patterns that replicate target tissue structures
  • Optimize designs through iterative improvements based on experimental feedback in relevant biological settings
  • Generate high-quality datasets via structured preclinical studies aligned with U.S. FDA and EMA regulatory expectations
  • Optimize designs through iterative improvements based on experimental feedback in relevant biological settings
  • Generate high-quality datasets via structured preclinical studies aligned with U.S. FDA and EMA regulatory expectations

CASE STUDIES

BIOPRINTING4HEALING

Is dedicated to creating advanced technology for precise additive manufacturing of cutaneous constructs, contributing to sustainable therapies for combating chronic wounds.

In collaboration with Vicomtech, Makby has developed a versatile set of 3D bioprinting software applications for the creation of patches with diverse patterns that govern factors such as porosity and internal structure. Additionally, the software regulates the movement parameters and printing temperatures of the print tools.

This innovative software application offers users a wider array of options and mechanisms for printing diverse patterns, ensuring the production of patches specifically designed to aid in the healing of wounds.

Produces an intelligent, multifunctional, and cost-effective 3D-printed wound dressing designed for the treatment of chronic wounds (CW). This innovative dressing aims to manage bacterial infection and inflammation, alleviate skin tension, and promote the stimulation of healing.

Within FORCE REPAIR, Vicomtech, through Makby has developed a user friendly control software and graphical user interface (GUI) tailored to hardware specifications. This software enables the parameterization of the 3D model for the wound dressing, facilitating the distribution of materials in three dimensions. Users can configure the internal structure (infill) of each region independently. Additionally, the software generates 3D printing trajectories (GCODE) necessary for fabricating the model using a customized bioprinter.

Vicomtech is a partner in the FORCE REPAIR project.

FORCE REPAIR is an initiative funded by the European Union’s Horizon Europe Research and Innovation programme under grant agreement N° 101092243.

TEAM

Makby is a spin-off of Vicomtech, established in response to research needs to find novel tools that facilitate and standardise the 3D bioprinting workflow.

Vicomtech is a BRTA partner technology center located in the North of Spain, whose mission is to respond to the needs of Applied Research, Development and Innovation in Information Technology, especially the convergence ofComputer Graphics and Computer Vision (VisualComputing), Data Analytics & Intelligence, InteractiveDigital Media and Language Technologies, of the companies and institutions in their environment, to face the new economic and social challenges, improving their competitiveness in a global market.

CONTACT US

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alessandro.scandurra@makby.com

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